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Difficulty clearing upper airway secretions (death rattle) is a frequent problem at the end of life. Treatment often includes the use of anticholinergic drugs.
Sep 9, 2012 · Anticholinergics, or antimuscarinic drugs, are drugs that competitively inhibit the action of acetylcholine at muscarinic receptors, leading to a blockade of the actions of the …
Although many studies have questioned the need for pharmacologic treatment of terminal secretions, anticholinergic agents are the most commonly used class of medications to treat …
May 5, 2025 · The use of anticholinergic agents to manage terminal secretions, often referred to as the death rattle, remains a nuanced and evolving area of end-of-life care.
Mar 5, 2023 · Utilize anticholinergic medications with caution, as the risk of side effects may outweigh the benefits of their use to lessen secretions. Common anticholinergic side effects …
Jan 19, 2025 · Glycopyrrolate is a muscarinic receptor antagonist and an essential anticholinergic agent in perioperative care and various medical settings. Clinicians use this medication to …
Mar 1, 2009 · Summary: Anticholinergic medications used to reduce noisy respirations from retained secretions in terminal patients include atropine, glycopyrrolate, scopolamine, and …
Mar 15, 2017 · Oropharyngeal secretions may lead to noisy breathing, sometimes referred to as a death rattle, which is common at the end of life. Providing anticipatory guidance helps families …
1.5.29 only consider anticholinergic medicines other than glycopyrronium bromide to manage drooling of saliva in people with Parkinson's disease if their risk of cognitive adverse effects is …
Jul 22, 2025 · For patients with excessive secretions, anticholinergic medications including glycopyrrolate, scopolamine, atropine, and hyoscyamine are the first-line pharmacological …
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